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Search Results for " interleukin 24 "
Targets Recommended: HDAC PDE Adenosine Receptor

3

抑制剂 & 化合物

15

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1083L Theophylline monohydrate

Quibron,茶碱一水合物

 HDAC; PDE; Adenosine Receptor Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Theophylline monohydrate (Quibron) 似乎抑制磷酸二酯酶和前列腺素的产生，调节钙通量和细胞内钙分布，并拮抗腺苷。茶碱是黄嘌呤的天然生物碱衍生物，从植物山茶花和小粒咖啡中分离出来。在生理上，该药剂可放松支气管平滑肌，产生血管舒张（脑血管除外），刺激中枢神经系统，刺激心肌，利尿，增加胃酸分泌；它还可以抑制炎症并改善横膈膜的收缩性。
T37331 Pyrrophenone

The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py...
T36668 Geranylgeranoic Acid

Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not primary mouse hepatocytes, when used at concentrations ranging from 1 to 20 μM. GGA (10 μM) induces apoptosis in Huh7 cellsvialoss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32).2It also...

化合物

Theophylline monohydrate
Cat.No: T1083L
Synonym: Quibron,茶碱一水合物
Target: HDAC, PDE, Adenosine Receptor
Pyrrophenone
Cat.No: T37331
Synonym:
Target:
Geranylgeranoic Acid
Cat.No: T36668
Synonym:
Target:
Species：
Human (14)
Mouse (1)
Expression System：
HEK293 Cells (12)
E. coli (2)
Baculovirus Insect Cells (1)
Tag：
C-His-Avi (9)
C-His (1)
C-mFc (1)
His (1)
N-6xHis (1)
N-His-Avi (1)
Tag Free (1)
Cat. No. Product Name Species Expression System
TMPY-02087 IL-24 Protein, Human, Recombinant (His)

C49A,IL10B,MOB5,ST16,MDA7,FISP,interleukin 24

Human HEK293 Cells
IL-24 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is A0A7R8C2Y5.
TMPY-05177 IL-24 Protein, Human, Recombinant (mFc)

白细胞介素,ST16,interleukin 24,白介素,MDA7,IL10B,C...

 Human HEK293 Cells
IL-24 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 44.6 kDa and the accession number is A0A7R8C2Y5.
TMPY-00493 IL-19 Protein, Human, Recombinant (His)

interleukin 19,Interleukin-19,IL-10C,NG.1,...

 Human Baculovirus Insect Cells
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the regulation of epidermal functions and inflammation. The expression of IL19 in biopsies of patients with active ulcerative colitis was increased compared with patients with quiescent ulcerative colitis and that colitis was attenuated in IL-19-deficient mice. The disruption of the e...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His)

Interferon γ-inducing factor,Interleukin-1 gamma,Ig...

 Mouse E. coli
Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPJ-00047 IL-31 Protein, Human, Recombinant

IL-31,Interleukin-31,白介素,白细胞介素,IL31

 Human E. coli
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. Human IL-31 cDNA encodes a 164 amino acid precursor that contains a 23 amino acid signal peptide and a 141 amino acid mature protein. Human and mouse IL-31 share 24% sequence identity in the mature region. IL-31 is mainly associated with activated T cells and is preferentially expressed by type 2 helper...
TMPK-01409 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Peptide Ready,MHC,HLA-A

 Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01473 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CT1.3,MAGE-3,MZ2-D,MZ2D,HLA-A2402,HLA-A*24...

 Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01487 HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi)

svn-2B,Survivin-2B,svn 2B

 Human HEK293 Cells
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
TMPK-01410 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)

HLA-A,MHC,Peptide Ready

 Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01486 HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Tetramer Protein, Human, MHC (His & Avi)

svn-2B,Survivin-2B,svn 2B

 Human HEK293 Cells
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
TMPK-01474 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01481 HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

svn 2B,svn-2B,Survivin-2B

 Human HEK293 Cells
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
TMPK-01472 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)

MAGE-3,CT1.3,Melanoma-associated antigen 3,MZ2D,MZ2-D,HLA-A*...

 Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01475 HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

HLA-A*24:02,Intron 4,gp100,GP100 Intron 4,Glycoprot...

 Human HEK293 Cells
Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A*0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and YLEPGPVTA peptide of  the gp100.
TMPK-01476 HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi)

HLA-A*24:02,P100,Glycoprotein 100,GP100 Intron 4,HL...

 Human HEK293 Cells
Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A*0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and YLEPGPVTA peptide of  the gp100.

重组蛋白

IL-24 Protein, Human, Recombinant (His)
Cat.No: TMPY-02087
Species: Human
Expression System: HEK293 Cells
IL-24 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05177
Species: Human
Expression System: HEK293 Cells
IL-19 Protein, Human, Recombinant (His)
Cat.No: TMPY-00493
Species: Human
Expression System: Baculovirus Insect Cells
IL-18 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01056
Species: Mouse
Expression System: E. coli
IL-31 Protein, Human, Recombinant
Cat.No: TMPJ-00047
Species: Human
Expression System: E. coli
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01409
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01473
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01487
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01410
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01486
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01474
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01481
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01472
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01475
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01476
Species: Human
Expression System: HEK293 Cells
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